Status of Hepatozoonosis in Wildlife: A Global Overview

[1] Alencar NX, Kohayagawa A, Santarem VA. Hepa-
tozoon canis infection of wild carnivores in Brazil.
Veterinary Parasitology. 1997 Jul 1;70(4):279-82.
[2] Allen KE, Li Y, Kaltenboeck B, Johnson EM, Re-
ichard MV, Panciera RJ, Little SE. Diversity of
Hepatozoon species in naturally infected dogs in
the southern United States. Veterinary Parasitol-
ogy. 2008 Jul 4;154(3-4):220-5.
[3] Al-Quraishy S, Abdel-Ghaffar F, Dkhil MA,
Abdel-Gaber R. Haemogregarines and criteria for
identi cation. Animals. 2021 Jan 12;11(1):170.
[4] Andre MR, Adania CH, Teixeira RH, Vargas
GH, Falcade M, Sousa L, Salles AR, Allegretti
SM, Felippe PA, Machado RZ. Molecular detec-
tion of Hepatozoon spp. in Brazilian and exotic
wild carnivores. Veterinary Parasitology. 2010 Oct
11;173(1-2):134-8.
[5] Andre MR, Denardi NC, de Sousa KC, Goncalves
LR, Henrique PC, Ontivero CR, Gonzalez IH,
Nery CV, Chagas CR, Monticelli C, de Santis AC.
Arthropod-borne pathogens circulating in free-
roaming domestic cats in a zoo environment in
Brazil. Ticks and tick-borne diseases. 2014 Sep
1;5(5):545-51.
[6] Baker HJ, Lindsey JR, Wesibroth SH, editors.
The laboratory rat: biology and diseases. Elsevier;
2013 Oct 2.
[7] Baneth GA, Samish M, Alekseev E, Aroch I,
Shkap V. Transmission of Hepatozoon canis to
dogs by naturally-fed or percutaneously-injected
Rhipicephalus sanguineus ticks. Journal of Para-
sitology. 2001 Jun 1;87(3):606-11.
[8] Battisti E, Zanet S, Khalili S, Trisciuoglio A, Her-
tel B, Ferroglio E. Molecular survey on vector-
borne pathogens in alpine wild carnivorans. Fron-
tiers in Veterinary Science. 2020 Jan 23;7:1.
[9] Bennett GF, Earle RA, Penzhorn BL. Or-
nithodoros peringueyi (Argasidae) and Xenop-
sylla trispinis (Siphonaptera), probable interme-
diate hosts of Hepatozoon atticorae of the South
African Cliff Swallow, Hirundo spilodera. Cana-
dian Journal of Zoology. 1992 Jan 1;70(1):188-90.
[10] Brumpt E. Contribution a l'etude d'hepatozoon
muris. Utilisation du xenodiagnostic pour
l'identi cation des especes d'hemogregarines.
Annales de Parasitologie Humaine et Comparee.
1946;21(1-2):1-24.
[11] Cardoso L, Cortes HC, Eyal O, Reis A, Lopes AP,
Vila-Vicosa MJ, Rodrigues PA, Baneth G. Molec-
ular and histopathological detection of Hepato-
zoon canis in red foxes (Vulpes vulpes) from Por-
tugal. Parasites & Vectors. 2014 Mar 24;7(1):113.
[12] Cassini R, Zanutto S, Di Regalbono AF, Gabrielli
S, Calderini P, Moretti A, Tampieri MP, Pietro-
belli M. Canine piroplasmosis in Italy: epidemi-
ological aspects in vertebrate and invertebrate
hosts. Veterinary parasitology. 2009 Oct 28;165(1-
2):30-5.
[13] Christophers SS. The sexual cycle of Leucocyto-
zoon canis in the tick. Office of the Superintendent
of Government Printing, India; 1907.
[14] Clark GM. Hepatozoon griseisciuri n. sp.; a new
species of Hepatozoon from the grey squirrel (Sci-
urus carolinensis Gmelin, 1788), with studies on
the life cycle. The Journal of parasitology. 1958
Feb 1;44(1):52-63.
Status of Hepatozoonosis in Wildlife: A Global Overview: 35{49 44
[15] Clark GW, Swinehart BR. Avian haematozoa
from the offshore islands of northern Mexico. Bul-
letin of the Wildlife Disease Association. 1969 Apr
1;5(2):111-2.
[16] Conceic~ao-Silva FM, Abranches P, Silva-Pereira
MC, Janz JG. Hepatozoonosis in foxes from
Portugal. Journal of wildlife diseases. 1988
Apr;24(2):344-7.
[17] Craig T, Smallwood J, Knauer K, et al. H.
canis infection in dogs: clinical, radiographic,
and hematologic  ndings. J Am Vet Med Assoc
1978;173(8):967-972.
[18] Criado-Fornelio A, Rey-Valeiron C, Buling A,
Barba-Carretero JC, Jefferies R, Irwin P. New
advances in molecular epizootiology of canine
hematic protozoa from Venezuela, Thailand
and Spain. Veterinary parasitology. 2007 Mar
31;144(3-4):261-9.
[19] Criado-Fornelio A, Ruas JL, Casado N, Farias
NA, Soares MP, Muller G, Brum JG, Berne
ME, Buling-Sara~na A, Barba-Carretero JC.
New molecular data on mammalian Hepatozoon
species (Apicomplexa: Adeleorina) from Brazil
and Spain. Journal of Parasitology. 2006 Feb
1;92(1):93-9.
[20] Cunningham MW, Yabsley MJ. Primer on tick-
borne diseases in exotic carnivores. Fowlers Zoo
and Wild Animal Medicine Current Therapy.
Philadelphia, USA, Saunders. 2011 Jul 11;7:458-
64.
[21] de Bortoli CP, Andre MR, Braga MD, Machado
RZ. Molecular characterization of Hepatozoon
sp. in cats from S~ao Lus Island, Maranh~ao,
northeastern Brazil. Parasitology Research. 2011
Oct;109(4):1189-92.
[22] de Castro Demoner L, Magro NM, da Silva MR,
de Paula Antunes JM, Calabuig CI, ODwyer LH.
Hepatozoon spp. infections in wild rodents in an
area of endemic canine hepatozoonosis in south-
eastern Brazil. Ticks and tick-borne diseases. 2016
Jul 1;7(5):859-64.
[23] de Castro Demoner L, Magro NM, da Silva MR,
de Paula Antunes JM, Calabuig CI, ODwyer LH.
Hepatozoon spp. infections in wild rodents in an
area of endemic canine hepatozoonosis in south-
eastern Brazil. Ticks and tick-borne diseases. 2016
Jul 1;7(5):859-64.
[24] De Monte T. Infection with Hepatozoon muris
Balf. (Protozoa, Adeleidae) in wild varieties of
Rattus norvegicus in Trieste. Schweizer Archiv fur
Tierheilkunde. 1971 Nov 1;113(11):654-9.
[25] de Sousa KC, Fernandes MP, Herrera HM, Ben-
evenute JL, Santos FM, Rocha FL, Barreto WT,
Macedo GC, Campos JB, Martins TF, de Andrade
Pinto PC. Molecular detection of Hepatozoon spp.
in domestic dogs and wild mammals in southern
Pantanal, Brazil with implications in the trans-
mission route. Veterinary Parasitology. 2017 Apr
15;237:37-46.
[26] Dezek D, Vojta L, Curkovic S, Lipej Z, Mihaljevic
Z, Cvetnic Z, Beck R. Molecular detection of Thei-
leria annae and Hepatozoon canis in foxes (Vulpes
vulpes) in Croatia. Veterinary parasitology. 2010
Sep 20;172(3-4):333-6.
[27] Diakou A, Dimzas D, Astaras C, Savvas I, Di Ce-
sare A, Morelli S, Neo tos , Migli D, Traversa
D. Clinical investigations and treatment outcome
in a European wildcat (Felis silvestris silvestris)
infected by cardio-pulmonary nematodes. Veteri-
nary Parasitology: Regional Studies and Reports.
2020 Jan 1; 19: 100357.
[28] Daz-Sanchez AA, Hofmann-Lehmann R, Meli
ML, Roblejo-Arias L, Fonseca-Rodrguez O,
Castillo AP, Ca~nizares EV, Rivero EL, Chilton
NB, Corona-Gonzalez B. Molecular detection and
characterization of Hepatozoon canis in stray dogs
from Cuba. Parasitology international. 2021 Feb
1;80:102200.
[29] Duscher GG, Fuehrer HP, Kubber-Heiss A. Fox
on the run{molecular surveillance of fox blood and
tissue for the occurrence of tick-borne pathogens
in Austria. Parasites & vectors. vectors. 2014 Nov
21;7(1):521.
[30] Duscher GG, Leschnik M, Fuehrer HP, Joachim A.
Wildlife reservoirs for vector-borne canine, feline
and zoonotic infections in Austria. International
Journal for Parasitology: Parasites and Wildlife.
2015 Apr 1;4(1):88-96.
[31] East ML, Wibbelt G, Lieckfeldt D, Ludwig A,
Goller K, Wilhelm K, Schares G, Thierer D, Hofer
H. A Hepatozoon species genetically distinct from
H. canis infecting spotted hyenas in the Serengeti
ecosystem, Tanzania. Journal of Wildlife Diseases.
2008 Jan 1;44(1):45-52.
[32] Ezeokoli CD, Ogunkoya AB, Abdullahi R, Tekdek
LB, Sannusi A, Ilemobade AA. Clinical and epi-
demiological studies on canine hepatozoonosis in
Zaria, Nigeria. Journal of Small Animal Practice.
1983 Jul;24(7):455-60.
[33] Ferrari G, Girardi M, Cagnacci F, Devineau O,
Tagliapietra V. First record of Hepatozoon spp.
in alpine wild rodents: Implications and perspec-
tives for transmission dynamics across the food
web. Microorganisms. 2022 Mar 25;10(4):712.
Avicenna Veterinary Research/ Vol. 1, No. 4, Winter 2025 45
[34] Fishman Z, Gonen L, Harrus S, Strauss-Ayali D,
King R, Baneth G. A serosurvey of Hepatozoon
canis and Ehrlichia canis antibodies in wild red
foxes (Vulpes vulpes) from Israel. Veterinary Par-
asitology. 2004 Jan 5;119(1):21-6.
[35] Forlano MD, Teixeira KR, Sco eld A, Elisei C,
Yotoko KS, Fernandes KR, Linhares GF, Ewing
SA, Massard CL. Molecular characterization of
Hepatozoon sp. from Brazilian dogs and its phy-
logenetic relationship with other Hepatozoon spp.
Veterinary Parasitology. 2007 Apr 10;145(1-2):21-
30.
[36] Gabrielli S, Kumlien S, Calderini P, Brozzi A, Iori
A, Cancrini G. The  rst report of Hepatozoon
canis identi ed in Vulpes vulpes and ticks from
Italy. Vector-borne and Zoonotic Diseases. 2010
Nov 1;10(9):855-9.
[37] Garcia-Vozmediano A, Krawczyk AI, Sprong H,
Rossi L, Ramassa E, Tomassone L. Ticks climb
the mountains: Ixodid tick infestation and in-
fection by tick-borne pathogens in the Western
Alps. Ticks and Tick-borne Diseases. 2020 Sep
1;11(5):101489.
[38] Garrett JJ, Kocan AA, Reichard MV, Panciera
RJ, Bahr RJ, Ewing SA. Experimental infection of
adult and juvenile coyotes with domestic dog and
wild coyote isolates of Hepatozoon americanum
(Apicomplexa: Adeleorina). Journal of Wildlife
Diseases. 2005 Jul 1;41(3):588-92.
[39] Gevrey J. Hepatozoonose canine. Rec Med Vet
1993;169(1):6.
[40] Gilman SE, Urban MC, Tewksbury J, Gilchrist
GW, Holt RD. A framework for community inter-
actions under climate change. Trends in ecology &
evolution. 2010 Jun 1;25(6):325-31.
[41] Gimenez C, Casado N, Criado-Fornelio A, de
Miguel FA, Dominguez-Pe~na el G. A molecular
survey of Piroplasmida and Hepatozoon isolated
from domestic and wild animals in Burgos (north-
ern Spain). Veterinary Parasitology. 2009 May
26;162(1-2):147-50.
[42] Hamskova Z, Silaghi C, Rudolf I, Venclkova K,
Mahrkova L, Slovak M, Mendel J, Blazejova H,
Berthova L, Kocianova E, Hubalek Z. Molecular
detection and phylogenetic analysis of Hepatozoon
spp. in questing Ixodes ricinus ticks and rodents
from Slovakia and Czech Republic. Parasitology
research. 2016 Oct;115(10):3897-904.
[43] Han H, Wu Y, Dong H, Zhu S, Li L, Zhao Q,
Wu D, Pei E, Wang Y, Huang B. First report of
Hepatozoon (Apicomplexa: Adeleorina) from king
ratsnakes (Elaphe carinata) in Shanghai, with de-
scription of a new species. Acta Parasitologica.
2015 Apr;60(2):266-74.
[44] Hill AG, Boyd SP, Clark NJ, Proboste T. Haemo-
protozoa in wild shortbeaked echidnas (Tachy-
glossus aculeatus). Australian Veterinary Journal.
2022 Mar;100(3):130-4.
[45] HHodzic A, Alic A, Beck R, Beck A, Huber D,
Otranto D, Baneth G, Duscher GG. Hepatozoon
martis n. sp. (Adeleorina: Hepatozoidae): Mor-
phological and pathological features of a Hepa-
tozoon species infecting martens (family Mustel-
idae). Ticks and tick-borne diseases. 2018 May
1;9(4):912-20.
[46] Hoogstraal H. The life cycle and incidence of Hep-
atozoon balfouri (Laveran, 1905) in Egyptian jer-
boas (Jaculus spp.) and mites (Haemolaelaps ae-
gyptius Keegan, 1956). The Journal of Protozool-
ogy. 1961 Aug;8(3):231-48.
[47] Inokuma H, Okuda M, Ohno K, Shimoda K, On-
ishi T. Analysis of the 18S rRNA gene sequence of
a Hepatozoon detected in two Japanese dogs. Vet-
erinary Parasitology. 2002 Jun 26;106(3):265-71.
[48] Ivanov A, Kanakov D. First case of canine hepa-
tozoonosis in Bulgaria. Bulg J Vet Med. 2003 May
28;6:43-6.
[49] James SP. On a parasite found in the white cor-
puscles of the blood of dogs. Office of the Super-
intendant of Government Printing, India; 1905.
[50] Ji N, Chen X, Liu G, Zhao S, Tan W, Liu G,
Zhang J,Wang Y. Theileria, Hepatozoon and Tae-
nia infection in great gerbils (Rhombomys opimus)
in northwestern China. International Journal for
Parasitology: Parasites and Wildlife. 2021 Aug
1;15:79-86.
[51] Jittapalapong S, Rungphisutthipongse O,
Maruyama S, Schaefer JJ, Stich RW. Detection
of Hepatozoon canis in stray dogs and cats in
Bangkok, Thailand. Annals of the New York
Academy of Sciences. 2006 Oct;1081(1):479-88.
[52] Johnson EM, Allen KE, Breshears MA, Panciera
RJ, Little SE, Ewing SA. Experimental transmis-
sion of Hepatozoon americanum to rodents. Vet-
erinary parasitology. 2008 Feb 14;151(2-4):164-9.
[53] Johnson EM, Allen KE, Panciera RJ, Ewing SA,
Little SE, Reichard MV. Field survey of rodents
for Hepatozoon infections in an endemic focus of
American canine hepatozoonosis. Veterinary Par-
asitology. 2007 Nov 30;150(1-2):27-32.
Status of Hepatozoonosis in Wildlife: A Global Overview: 35{49 46
[54] Johnson PT, Dobson A, Lafferty KD, Marcogliese
DJ, Memmott J, Orlofske SA, Poulin R, Thielt-
ges DW. When parasites become prey: ecologi-
cal and epidemiological signi cance of eating par-
asites. Trends in ecology & evolution. 2010 Jun
1;25(6):362-71.
[55] Junsiri W, Kamkong P, Taweethavonsawat P.
First molecular detection and genetic diversity
of Hepatozoon sp. (Apicomplexa) and Brugia
sp.(Nematoda) in a crocodile monitor in Nakhon
Pathom, Thailand. Scienti c reports. 2024 Feb
12;14(1):3526.
[56] Karbowiak G, Rychlik L, Nowakowski W, Wita
I. Natural infections of small mammals with
blood parasites on the borderland of boreal and
temperate forest zones. Acta Theriologica. 2005
Mar;50(1):31-42.
[57] Khoshnegah J, Mohri M, Movassaghi AR,
Mehrjerdi HK. The  rst report of Hepatozoon ca-
nis infection of a dog in Iran. Comparative Clinical
Pathology. 2009 Nov;18(4):455-8.
[58] Kocan AA, Cummings CA, Panciera RJ, Mathew
JS, Ewing SA, Barker RW. Naturally occur-
ring and experimentally transmitted Hepatozoon
americanum in coyotes from Oklahoma. Journal
of Wildlife Diseases. 2000 Jan 1;36(1):149-53.
[59] Kolangath SM, Upadhye SV, Dhoot VM, Pawshe
MD, Shalini AS, Kolangath RM. Molecular inves-
tigation and clinical management of Hepatozoon
Canis infection in an Indian jackala case report.
BMC Veterinary Research. 2022 Apr 20;18(1):144.
[60] Kubo M, Nagataki M, Agatsuma T, Sakai H,
Masegi T, Panciera RJ, Yanai T. Parasitological
and molecular features of the Hepatozoon species
in the myocardium of Japanese Martens (Martes
melampus melampus). Journal of Parasitology.
2009 Dec 1;95(6):1496-502.
[61] Kurucki M, Tomanovic S, Sukara R, Cirovic
D. High prevalence and genetic variability of
Hepatozoon canis in grey wolf (Canis lupus L.
1758) population in Serbia. Animals. 2022 Nov
29;12(23):3335.
[62] Laakkonen J, Sukura A, Oksanen A, Henttonen
H, Soveri T. Haemogregarines of the genus Hepa-
tozoon (Apicomplexa: Adeleina) in rodents from
northern Europe. Folia parasitologica. 2001 Jan
1;48(4):263-7.
[63] Lavier G, Callot J. Hepatozoon burnandi n.
sp, hemogregarine parasite de. Tarentola mauri-
tanica. Archives de l'Institut Pasteur de Tunis.
1938;27:444-8.
[64] Lewis JE, Wagner ED. Hepatozoon sauromali sp.
n., a hemogregarine from the chuckwalla (Sauro-
malus spp.) with notes on the life history. The
Journal of Parasitology. 1964 Feb 1:11-4.
[65] Lindblad-Toh K, Wade CM, Mikkelsen TS, Karls-
son EK, Jaffe DB, Kamal M, Clamp M, Chang JL,
Kulbokas III EJ, Zody MC, Mauceli E. Genome
sequence, comparative analysis and haplotype
structure of the domestic dog. Nature. 2005 Dec
8;438(7069):803-19.
[66] Mackerras MJ. The life of a Hepatozoon (Sporo-
zoa: Adeleidea) of varanid Lizards in Aus-
tralia. Australian Journal of Zoology. 1962 Mar
1;10(1):35-44.
[67] Maia JP, Alvares F, Boratynski Z, Brito JC, Leite
JV, Harris DJ. Molecular assessment of Hepato-
zoon (Apicomplexa: Adeleorina) infections in wild
canids and rodents from North Africa, with im-
plications for transmission dynamics across taxo-
nomic groups. Journal of Wildlife Diseases. 2014
Oct 1;50(4):837-48.
[68] Majlathova V, Hurnkova Z, Majlath I, Petko B.
Hepatozoon canis infection in Slovakia: imported
or autochthonous?. Vector-Borne and Zoonotic
Diseases. 2007 Jun 1;7(2):199-202.
[69] Matsuo K, Uetsu H, Takashima Y, Abe N. High
occurrence of Sarcocystis infection in Sika deer
Cervus nippon centralis and Japanese wild boar
Sus scrofa leucomystax and molecular character-
ization of Sarcocystis and Hepatozoon isolates
from their muscles.
[70] Menn B, Lorentz S, Naucke TJ. Imported and
travelling dogs as carriers of canine vector-borne
pathogens in Germany. Parasites vectors. 2010
Apr 8;3(1):34.
[71] Mercer SH, Jones LP, Rappole JH, Twedt D,
Laack LL, Craig TM. Hepatozoon sp. in wild car-
nivores in Texas. Journal of Wildlife Diseases.
1988 Jul;24(3):574-6.
[72] Merino S, Martnez J, Masello JF, Bedolla Y,
Quillfeldt P. First molecular characterization of a
Hepatozoon species (Apicomplexa: Hepatozoidae)
infecting birds and description of a new species in-
fecting storm petrels (Aves: Hydrobatidae). The
Journal of parasitology. 2014 Jun 1;100(3):338-43.
[73] Merino S, Vasquez RA, Martnez J, Celis-Diez JL,
Gutierrez-Jimenez L, Ippi S, Sanchez-Monsalvez
I, Martnez-De La Puente J. Molecular charac-
terization of an ancient Hepatozoon species par-
asitizing the `living fossil'marsupial `Monito del
Avicenna Veterinary Research/ Vol. 1, No. 4, Winter 2025 47
Monte'Dromiciops gliroides from Chile. Biolog-
ical Journal of the Linnean Society. 2009 Nov
1;98(3):568-76.
[74] Miller WW. Hepatozoon perniciosum (ng, n. sp.);
a haemogregarine pathogenic for white rats; with
a description of the sexual cycle in the intermedi-
ate host, a mite (Lelaps echidninus). (No Title).
1908.
[75] Modry D, Hofmannova L, Papezk P, Majerova
K, Votypka J, Honig V, Ruzek D, Hrazdilova
K. Hepatozoon in Eurasian red squirrels Sciu-
rus vulgaris, its taxonomic identity, and phylo-
genetic placement. Parasitology Research. 2021
Aug;120(8):2989-93.
[76] Motta RO, Cunha LM, Leite RC, Da Silva IJ,
Pinto AC, Braga M, Da Cunha AP, De Oliveira
PR. Hepatozoon ssp. (Apicomplexa: Hepato-
zoidae) infection and selected hematological values
of the neotropical rattlesnake, Crotalus durissus
collilineatus (Linnaeus, 1758) (Serpentes: Viperi-
dae), from Brazil. Journal of Zoo and Wildlife
Medicine. 2011 Sep;42(3):399-407.
[77] Murata T, Inoue M, Tateyama S, Taura Y,
Nakama S. Vertical transmission of Hepatozoon
canis in dogs. Journal of Veterinary Medical Sci-
ence. 1993 Oct 15;55(5):867-8.
[78] Odwyer LH, Massard CL, de Souza JC. Hepato-
zoon canis infection associated with dog ticks of
rural areas of Rio de Janeiro State, Brazil. Veteri-
nary Parasitology. 2001 Jan 1;94(3):143-50.
[79] O'Dwyer LH. Brazilian canine hepatozoonosis.
Revista brasileira de parasitologia veterinria.
2011;20:181-93.
[80] Paperna I, Lainson R. Hepatozoon cf. terzii (Sam-
bon Seligman, 1907) infection in the snake Boa
constrictor constrictor from north Brazil: trans-
mission to the mosquito Culex quinquefasciatus
and the lizard Tropidurus torquatus. Parasite.
2004 Jun 1;11(2):175-81.
[81] Pawar RM, Poornachandar A, Arun AS, Manikan-
dan S, Shivaji S. Molecular prevalence and charac-
terization of Hepatozoon ursi infection in Indian
sloth bears (Melursus ursinus). Veterinary Para-
sitology. 2011 Dec 15;182(2-4):329-32.
[82] Pawar RM, Poornachandar A, Srinivas P, Rao
KR, Lakshmikantan U, Shivaji S. Molecular char-
acterization of Hepatozoon spp. infection in en-
dangered Indian wild felids and canids. Veterinary
Parasitology. 2012 May 25;186(3-4):475-9.
[83] Pawelczyk A, Bajer A, Behnke JM, Gilbert FS,
Sinski E. Factors affecting the component com-
munity structure of haemoparasites in common
voles (Microtus arvalis) from the Mazury Lake
District region of Poland. Parasitology Research.
2004 Mar;92(4):270-84.
[84] Peirce MA. A checklist of the valid avian
species of Babesia (Apicomplexa: Piroplas-
morida), Haemoproteus, Leucocytozoon (Apicom-
plexa: Haemosporida), and Hepatozoon (Apicom-
plexa: Haemogregarinidae). Journal of Natural
History. 2005 Dec 23;39(42):3621-32.
[85] Perles L, Roque AL, DAndrea PS, Lemos ER, San-
tos AF, Morales AC, Machado RZ, Andr MR. Ge-
netic diversity of Hepatozoon spp. in rodents from
Brazil. Scienti c Reports. 2019 Jul 12;9(1):10122.
[86] Ploeg RJ, Nicolson V, Pyne M, Webb R,
O'donoghue P. Hepatozoon tachyglossi in the
short-beaked echidna (Tachyglossus aculeatus).
Australian veterinary journal. 2008 May 1;86(5).
[87] Rajamanickam C, Wiesenhutter E, Zin FM,
Hamid J. The incidence of canine haematozoa
in Peninsular Malaysia. Veterinary parasitology.
1985 Jan 1;17(2):151-7.
[88] Rigo K, Majoros G, Szekeres S, Molnar I, Jablon-
szky M, Majlathova V, Majlath I, Foldvari
G. Identi cation of Hepatozoon erhardovae
Krampitz, 1964 from bank voles (Myodes glare-
olus) and  eas in Southern Hungary. Parasitology
research. 2016 Jun;115(6):2409-13.
[89] Rizzoli A, Tagliapietra V, Cagnacci F, Marini G,
Arnoldi D, Rosso F, Rosa R. Parasites and wildlife
in a changing world: The vector-host-pathogen in-
teraction as a learning case. International Journal
for Parasitology: Parasites and Wildlife. 2019 Aug
1;9:394-401.
[90] Rubini AS, dos Santos Paduan K, Perez RR, Ri-
bolla PE, ODwyer LH. Molecular characterization
of feline Hepatozoon species from Brazil. Veteri-
nary Parasitology. 2006 Apr 15;137(1-2):168-71.
[91] Sebek Z. Blood parasites of small mammals
in western Hungary. Parasitologia Hungarica.
1978;11:17-22.
[92] Shimizu T, Yasuda N, Kono I, Koyama T. Fa-
tal infection of Hepatozoon-like organisms in the
young captive cranes (Grus monacha). Memoirs of
the Faculty of Agriculture-Kagoshima University
(Japan). 1987;23.
[93] Shkap V, Baneth G, Pipano E. Circulating anti-
bodies to Hepatozoon canis demonstrated by im-
muno uorescence. Journal of Veterinary Diagnos-
tic Investigation. 1994 Jan;6(1):121-3.
Status of Hepatozoonosis in Wildlife: A Global Overview: 35{49 48
[94] Simpson VR, Birtles RJ, Bown KJ, Panciera
RJ, Butler H, Davison N. Hepatozoon species
infection in wild red squirrels (Sciurus vulgaris)
on the Isle of Wight. Veterinary Record. 2006
Aug;159(7):202-5.
[95] Simpson VR, Panciera RJ, Hargreaves J, McGarry
JW, Scholes SF, Bown KJ, Birtles RJ. Myocardi-
tis and myositis due to infection with Hepatozoon
species in pine martens (Martes martes) in Scot-
land. Veterinary Record. 2005 Apr;156(14):442-6.
[96] Soares HS, Marcili A, Barbieri AR, Minervino AH,
Moreira TR, Gennari SM, Labruna MB. Novel
piroplasmid and Hepatozoon organisms infecting
the wildlife of two regions of the Brazilian Ama-
zon. International Journal for Parasitology: Para-
sites and Wildlife. 2017 Aug 1;6(2):115-21.
[97] Starkey LA, Panciera RJ, Paras K, Allen KE,
Reiskind MH, Reichard MV, Johnson EM, Lit-
tle SE. Genetic diversity of Hepatozoon spp. in
coyotes from the south-central United States. The
Journal of Parasitology. 2013 Apr 1;99(2):375-8.
[98] Sumrandee C, Baimai V, Trinachartvanit W,
Ahantarig A. Hepatozoon and Theileria species
detected in ticks collected from mammals and
snakes in Thailand. Ticks and tick-borne diseases.
2015 Apr 1;6(3):309-15.
[99] Tome B, Maia JP, Salvi D, Brito JC, Carretero
MA, Perera A, Meimberg H, Harris DJ. Pat-
terns of genetic diversity in Hepatozoon spp.
infecting snakes from North Africa and the
Mediterranean Basin. Systematic Parasitology.
2014 Mar;87(3):249-58.
[100] Tome B, Rato C, Harris DJ, Perera A. High di-
versity of Hepatozoon spp. in geckos of the genus
Tarentola. The Journal of Parasitology. 2016 Aug
1;102(4):476-80.
[101] Uiterwijk M, Vojta L, Sprem N, Beck A, Jurkovic
D, Kik M, Duscher GG, Hodzic A, Reljic S, Sprong
H, Beck R. Diversity of Hepatozoon species in wild
mammals and ticks in Europe. Parasites & Vec-
tors. 2023 Jan 24;16(1):27.
[102] Urban MC, Bocedi G, Hendry AP, Mihoub JB,
Peer G, Singer A, Bridle JR, Crozier LG, De
Meester L, Godsoe W, Gonzalez A. Improving the
forecast for biodiversity under climate change. Sci-
ence. 2016 Sep 9;353(6304): aad8466.
[103] Valkiunas G, Mobley K, Iezhova TA. Hepatozoon
ellisgreineri n. sp. (Hepatozoidae): description of
the  rst avian apicomplexan blood parasite in-
habiting granulocytes. Parasitology research. 2016
Feb;115(2):609-13.
[104] Vilcins IM, Ujvari B, Old JM, Deane E. Molecu-
lar and morphological description of a Hepatozoon
species in reptiles and their ticks in the Northern
Territory, Australia. Journal of Parasitology. 2009
Apr 1;95(2):434-42.
[105] Vilhena H, Martinez-Daz VL, Cardoso L, Vieira
L, Altet L, Francino O, Pastor J, Silvestre-Ferreira
AC. Feline vector-borne pathogens in the north
and centre of Portugal. Parasites & Vectors. 2013
Apr 15;6(1):99.
[106] Vincent-Johnson NA, Macintire DK, Lindsay
DS, Lenz SD, Baneth G, Shkap V, Blagburn BL.
A new Hepatozoon species from dogs: description
of the causative agent of canine hepatozoonosis in
North America. The Journal of parasitology. 1997
Dec 1:1165-72.
[107] Wolf RW, Aragona M, Munoz-Leal S, Pinto LB,
Melo AL, Braga IA, dos Santos Costa J, Martins
TF, Marcili A, de Campos Pacheco R, Labruna
MB. Novel Babesia and Hepatozoon agents in-
fecting non-volant small mammals in the Brazil-
ian Pantanal, with the  rst record of the tick Or-
nithodoros guaporensis in Brazil. Ticks and tick-
borne Diseases. 2016 Apr 1;7(3):449-56.
[108] Wozniak EJ, Telford Jr SR, DeNardo DF,
McLaughlin GL, Butler JF. Granulomatous hep-
atitis associated with Hepatozoon sp. meronts in
a southern water snake (Nerodia fasciata pictiven-
tris). Journal of Zoo and Wildlife Medicine. 1998
Mar 1:68-71.
[109] Yamamoto M, Tokiwa T, Tobiume M, Aka-
matsu S, Matsuo K, Moribe J, Ike K. Hepatozoon
apri n. sp. (Adeleorina: Hepatozoidae) from the
Japanese wild boar Sus scrofa leucomystax (Mam-
malia: Cetartiodactyla). International Journal for
Parasitology: Parasites and Wildlife. 2017 Dec
1;6(3):354-60.
[110] Yu JH, Durrant KL, Liu S, Carlin EP, Wang
C, Rodriguez J, Bratthauer A, Walsh T, Vali-
tutto MT, Fine L, Murray S. First report of a
novel Hepatozoon sp. in giant pandas (Ailuropoda
melanoleuca). EcoHealth. 2019 Jun 15;16(2):338-
45.
[111] Zechmeisterova K, Javanbakht H, Kvicerova J,
Siroky P. Against growing synonymy: Identi ca-
tion pitfalls of Hepatozoon and Schellackia demon-
strated on North Iranian reptiles. European Jour-
nal of Protistology. 2021 Jun 1;79:125780.
[112] Zeinali M, Malekifard F, Rakhshanpour A,
Yakhchali M. Study on Hepatozoon canis in dogs
in Urmia region. Iranian Journal of Animal Sci-
ence. 2022 Jan 21;52(4):253-60.